GO Annotations Graph

• Symbol: Slc4a2
• Name: solute carrier family 4 (anion exchanger), member 2
• ID: MGI:109351

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0015297	antiporter activity	IEA	J:60000
Molecular Function	GO:0015108	chloride transmembrane transporter activity	IDA	J:150322
Molecular Function	GO:0140900	chloride:bicarbonate antiporter activity	ISO	J:164563
Molecular Function	GO:0140900	chloride:bicarbonate antiporter activity	IDA	J:331356
Molecular Function	GO:0140900	chloride:bicarbonate antiporter activity	IMP	J:331915
Molecular Function	GO:0140900	chloride:bicarbonate antiporter activity	ISO	J:155856
Molecular Function	GO:0140900	chloride:bicarbonate antiporter activity	IDA	J:331357
Molecular Function	GO:0140900	chloride:bicarbonate antiporter activity	IMP	J:193823
Molecular Function	GO:0019899	enzyme binding	ISO	J:155856
Molecular Function	GO:0008509	monoatomic anion transmembrane transporter activity	IEA	J:72247
Molecular Function	GO:0005452	solute:inorganic anion antiporter activity	IEA	J:72247
Molecular Function	GO:0022857	transmembrane transporter activity	IBA	J:265628
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0016324	apical plasma membrane	IBA	J:265628
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:155856
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:193823
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:331356
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:331357
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:143261
Cellular Component	GO:0016323	basolateral plasma membrane	IBA	J:265628
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:176751
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:87933
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:87933
Cellular Component	GO:0016020	membrane	IDA	J:150322
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:0097186	amelogenesis	IDA	J:306590
Biological Process	GO:0015701	bicarbonate transport	IBA	J:265628
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0006821	chloride transport	IDA	J:150322
Biological Process	GO:0006820	monoatomic anion transport	IEA	J:72247
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0043377	negative regulation of CD8-positive, alpha-beta T cell differentiation	IMP	J:331915
Biological Process	GO:2000565	negative regulation of CD8-positive, alpha-beta T cell proliferation	IMP	J:331915
Biological Process	GO:0030316	osteoclast differentiation	IMP	J:143261
Biological Process	GO:0030316	osteoclast differentiation	ISO	J:164563
Biological Process	GO:0070175	positive regulation of enamel mineralization	IDA	J:306590
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	IMP	J:193823
Biological Process	GO:0045124	regulation of bone resorption	IMP	J:193823
Biological Process	GO:0051453	regulation of intracellular pH	ISO	J:155856
Biological Process	GO:0051453	regulation of intracellular pH	IBA	J:265628
Biological Process	GO:0007283	spermatogenesis	IMP	J:88196
Biological Process	GO:0055085	transmembrane transport	IBA	J:265628