GO Annotations Graph

• Symbol: Ncs1
• Name: neuronal calcium sensor 1
• ID: MGI:109166

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	ISO	J:155856
Molecular Function	GO:0005509	calcium ion binding	IBA	J:265628
Molecular Function	GO:0005509	calcium ion binding	TAS	J:67580
Molecular Function	GO:0005509	calcium ion binding	TAS	J:38125
Molecular Function	GO:0008048	calcium sensitive guanylate cyclase activator activity	IBA	J:265628
Molecular Function	GO:0000287	magnesium ion binding	ISO	J:155856
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0005245	voltage-gated calcium channel activity	ISO	J:155856
Cellular Component	GO:0030424	axon	IDA	J:38125
Cellular Component	GO:0044305	calyx of Held	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0030425	dendrite	IDA	J:38125
Cellular Component	GO:0031045	dense core granule	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0005794	Golgi apparatus	IEA	J:60000
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0098794	postsynapse	ISO	J:155856
Cellular Component	GO:0099524	postsynaptic cytosol	ISO	J:155856
Cellular Component	GO:0099523	presynaptic cytosol	ISO	J:155856
Cellular Component	GO:0045202	synapse	IEA	J:60000
Biological Process	GO:0048015	phosphatidylinositol-mediated signaling	ISO	J:155856
Biological Process	GO:0045921	positive regulation of exocytosis	ISO	J:155856
Biological Process	GO:0050806	positive regulation of synaptic transmission	TAS	J:38125
Biological Process	GO:0010975	regulation of neuron projection development	ISO	J:155856
Biological Process	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	ISO	J:155856
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	ISO	J:155856