GO Annotations Graph

• Symbol: Rgn
• Name: regucalcin
• ID: MGI:108024

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	ISO	J:164563
Molecular Function	GO:0005509	calcium ion binding	ISO	J:155856
Molecular Function	GO:0005509	calcium ion binding	IBA	J:265628
Molecular Function	GO:0030234	enzyme regulator activity	IEA	J:72247
Molecular Function	GO:0004341	gluconolactonase activity	ISO	J:155856
Molecular Function	GO:0004341	gluconolactonase activity	IDA	J:195848
Molecular Function	GO:0004341	gluconolactonase activity	ISO	J:164563
Molecular Function	GO:0004341	gluconolactonase activity	IBA	J:265628
Molecular Function	GO:0004341	gluconolactonase activity	IMP	J:108295
Molecular Function	GO:0004341	gluconolactonase activity	IMP	J:108295
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008270	zinc ion binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:79342
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:79342
Biological Process	GO:0006874	intracellular calcium ion homeostasis	ISO	J:155856
Biological Process	GO:0019853	L-ascorbic acid biosynthetic process	IDA	J:195848
Biological Process	GO:0019853	L-ascorbic acid biosynthetic process	IBA	J:265628
Biological Process	GO:0019853	L-ascorbic acid biosynthetic process	IMP	J:108295
Biological Process	GO:0019853	L-ascorbic acid biosynthetic process	IMP	J:108295
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:155856
Biological Process	GO:1903011	negative regulation of bone development	ISO	J:155856
Biological Process	GO:1903611	negative regulation of calcium-dependent ATPase activity	ISO	J:155856
Biological Process	GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity	ISO	J:155856
Biological Process	GO:2000279	negative regulation of DNA biosynthetic process	ISO	J:155856
Biological Process	GO:1903625	negative regulation of DNA catabolic process	ISO	J:155856
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	ISO	J:155856
Biological Process	GO:1901318	negative regulation of flagellated sperm motility	ISO	J:155856
Biological Process	GO:0034260	negative regulation of GTPase activity	ISO	J:155856
Biological Process	GO:1903634	negative regulation of leucine-tRNA ligase activity	ISO	J:155856
Biological Process	GO:0045019	negative regulation of nitric oxide biosynthetic process	ISO	J:155856
Biological Process	GO:0032515	negative regulation of phosphoprotein phosphatase activity	ISO	J:155856
Biological Process	GO:0006469	negative regulation of protein kinase activity	ISO	J:155856
Biological Process	GO:0001933	negative regulation of protein phosphorylation	ISO	J:155856
Biological Process	GO:1902679	negative regulation of RNA biosynthetic process	ISO	J:155856
Biological Process	GO:0032781	positive regulation of ATP-dependent activity	ISO	J:155856
Biological Process	GO:1901896	positive regulation of ATPase-coupled calcium transmembrane transporter activity	ISO	J:155856
Biological Process	GO:1903629	positive regulation of dUTP diphosphatase activity	ISO	J:155856
Biological Process	GO:0045723	positive regulation of fatty acid biosynthetic process	ISO	J:155856
Biological Process	GO:0010907	positive regulation of glucose metabolic process	ISO	J:155856
Biological Process	GO:0043547	positive regulation of GTPase activity	ISO	J:155856
Biological Process	GO:0010922	positive regulation of phosphatase activity	ISO	J:155856
Biological Process	GO:1903052	positive regulation of proteolysis involved in protein catabolic process	ISO	J:155856
Biological Process	GO:1901671	positive regulation of superoxide dismutase activity	ISO	J:155856
Biological Process	GO:0010867	positive regulation of triglyceride biosynthetic process	ISO	J:155856
Biological Process	GO:0050848	regulation of calcium-mediated signaling	ISO	J:155856
Biological Process	GO:0007283	spermatogenesis	ISO	J:155856