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GO Annotations Graph
Symbol
Name
ID
Slc8a2
solute carrier family 8 (sodium/calcium exchanger), member 2
MGI:107996

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0015297antiporter activityIEAJ:60000
Molecular FunctionGO:0015085calcium ion transmembrane transporter activityIMPJ:136458
Molecular FunctionGO:1905060calcium:monoatomic cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentrationISOJ:155856
Molecular FunctionGO:0005432calcium:sodium antiporter activityIMPJ:84050
Molecular FunctionGO:0005432calcium:sodium antiporter activityISOJ:155856
Molecular FunctionGO:0005432calcium:sodium antiporter activityIBAJ:265628
Molecular FunctionGO:0005516calmodulin bindingIEAJ:60000
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0015081sodium ion transmembrane transporter activityISOJ:155856
Cellular ComponentGO:0030424axonISOJ:155856
Cellular ComponentGO:0030424axonIBAJ:265628
Cellular ComponentGO:0043679axon terminusIMPJ:271785
Cellular ComponentGO:0042995cell projectionISOJ:155856
Cellular ComponentGO:0030425dendriteISOJ:155856
Cellular ComponentGO:0043197dendritic spineISOJ:155856
Cellular ComponentGO:0016020membraneIEAJ:72247
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0005874microtubuleISOJ:155856
Cellular ComponentGO:0005739mitochondrionISOJ:155856
Cellular ComponentGO:0043025neuronal cell bodyISOJ:155856
Cellular ComponentGO:0005886plasma membraneIMPJ:84050
Cellular ComponentGO:0005886plasma membraneISOJ:155856
Cellular ComponentGO:0098794postsynapseIBAJ:265628
Cellular ComponentGO:0014069postsynaptic densityIMPJ:271785
Cellular ComponentGO:0045211postsynaptic membraneISOJ:155856
Cellular ComponentGO:0098793presynapseISOJ:164563
Cellular ComponentGO:0042383sarcolemmaIBAJ:265628
Cellular ComponentGO:0045202synapseIDAJ:271785
Biological ProcessGO:1990034calcium ion export across plasma membraneISOJ:155856
Biological ProcessGO:1990034calcium ion export across plasma membraneIMPJ:136458
Biological ProcessGO:0098703calcium ion import across plasma membraneISOJ:155856
Biological ProcessGO:0098703calcium ion import across plasma membraneIBAJ:265628
Biological ProcessGO:0070588calcium ion transmembrane transportISOJ:155856
Biological ProcessGO:0070588calcium ion transmembrane transportIMPJ:84050
Biological ProcessGO:0006816calcium ion transportIEAJ:72247
Biological ProcessGO:0006816calcium ion transportIEAJ:60000
Biological ProcessGO:0060402calcium ion transport into cytosolISOJ:155856
Biological ProcessGO:0007154cell communicationIEAJ:72247
Biological ProcessGO:0050890cognitionIMPJ:282717
Biological ProcessGO:0006874intracellular calcium ion homeostasisIMPJ:84050
Biological ProcessGO:0006874intracellular calcium ion homeostasisISOJ:155856
Biological ProcessGO:0006874intracellular calcium ion homeostasisIMPJ:271785
Biological ProcessGO:0007612learningIMPJ:84050
Biological ProcessGO:0007611learning or memoryIMPJ:271785
Biological ProcessGO:0060291long-term synaptic potentiationIMPJ:84050
Biological ProcessGO:0060291long-term synaptic potentiationIMPJ:271785
Biological ProcessGO:0007613memoryIMPJ:84050
Biological ProcessGO:0098815modulation of excitatory postsynaptic potentialIMPJ:271785
Biological ProcessGO:0006811monoatomic ion transportIEAJ:60000
Biological ProcessGO:0070050neuron cellular homeostasisIMPJ:136458
Biological ProcessGO:0071902positive regulation of protein serine/threonine kinase activityIMPJ:271785
Biological ProcessGO:0099608regulation of action potential firing patternIMPJ:136458
Biological ProcessGO:0106056regulation of calcineurin-mediated signalingIMPJ:271785
Biological ProcessGO:0051480regulation of cytosolic calcium ion concentrationIMPJ:136458
Biological ProcessGO:0010468regulation of gene expressionIMPJ:271785
Biological ProcessGO:0010468regulation of gene expressionIMPJ:271785
Biological ProcessGO:0048172regulation of short-term neuronal synaptic plasticityIMPJ:84050
Biological ProcessGO:0002931response to ischemiaIMPJ:136458
Biological ProcessGO:0035725sodium ion transmembrane transportIMPJ:84050
Biological ProcessGO:0035725sodium ion transmembrane transportISOJ:155856
Biological ProcessGO:0035725sodium ion transmembrane transportIBAJ:265628
Biological ProcessGO:0006814sodium ion transportISOJ:155856
Biological ProcessGO:0050808synapse organizationIMPJ:271785
Biological ProcessGO:0055085transmembrane transportIEAJ:72247

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory