GO Annotations Graph

• Symbol: Cav3
• Name: caveolin 3
• ID: MGI:107570

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0043014	alpha-tubulin binding	IDA	J:126515
Molecular Function	GO:0005246	calcium channel regulator activity	ISO	J:164563
Molecular Function	GO:0071253	connexin binding	IPI	J:190290
Molecular Function	GO:0071253	connexin binding	ISO	J:164563
Molecular Function	GO:0071253	connexin binding	IBA	J:265628
Molecular Function	GO:0019899	enzyme binding	ISO	J:155856
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:164563
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:155856
Molecular Function	GO:0060090	molecular adaptor activity	IBA	J:265628
Molecular Function	GO:0050998	nitric-oxide synthase binding	ISO	J:155856
Molecular Function	GO:0019870	potassium channel inhibitor activity	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:109447
Molecular Function	GO:0005515	protein binding	IPI	J:263460
Molecular Function	GO:0005515	protein binding	IPI	J:206498
Molecular Function	GO:0005515	protein binding	IPI	J:168498
Molecular Function	GO:0005515	protein binding	IPI	J:168498
Molecular Function	GO:0005515	protein binding	IPI	J:95586
Molecular Function	GO:0005515	protein binding	IPI	J:33699
Molecular Function	GO:0005515	protein binding	IPI	J:86955
Molecular Function	GO:0005515	protein binding	IPI	J:93830
Molecular Function	GO:0005515	protein binding	IPI	J:150684
Molecular Function	GO:0005515	protein binding	IPI	J:107908
Molecular Function	GO:0005515	protein binding	IPI	J:66004
Molecular Function	GO:0005515	protein binding	IPI	J:160150
Molecular Function	GO:0005515	protein binding	IPI	J:95586
Molecular Function	GO:0005515	protein binding	IPI	J:66004
Molecular Function	GO:0005515	protein binding	IPI	J:150684
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:164563
Molecular Function	GO:0017080	sodium channel regulator activity	ISO	J:164563
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:164563
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:155856
Molecular Function	GO:0044325	transmembrane transporter binding	IBA	J:265628
Molecular Function	GO:0044325	transmembrane transporter binding	IPI	J:168498
Molecular Function	GO:0044325	transmembrane transporter binding	IPI	J:168498
Molecular Function	GO:0044325	transmembrane transporter binding	IPI	J:144069
Cellular Component	GO:0005901	caveola	ISO	J:155856
Cellular Component	GO:0005901	caveola	IDA	J:206498
Cellular Component	GO:0005901	caveola	IDA	J:217280
Cellular Component	GO:0005901	caveola	ISO	J:155856
Cellular Component	GO:0005901	caveola	IBA	J:265628
Cellular Component	GO:0005901	caveola	IDA	J:37694
Cellular Component	GO:0005901	caveola	IDA	J:79453
Cellular Component	GO:0005901	caveola	IDA	J:168498
Cellular Component	GO:0005901	caveola	IDA	J:91905
Cellular Component	GO:0005901	caveola	ISO	J:73065
Cellular Component	GO:0005901	caveola	IDA	J:109447
Cellular Component	GO:0005901	caveola	ISO	J:73065
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0016010	dystrophin-associated glycoprotein complex	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:189648
Cellular Component	GO:0005925	focal adhesion	IBA	J:265628
Cellular Component	GO:0005794	Golgi apparatus	IEA	J:60000
Cellular Component	GO:0014704	intercalated disc	ISO	J:155856
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016020	membrane	IDA	J:93830
Cellular Component	GO:0016020	membrane	IDA	J:63998
Cellular Component	GO:0016020	membrane	IDA	J:170926
Cellular Component	GO:0045121	membrane raft	IDA	J:69965
Cellular Component	GO:0031594	neuromuscular junction	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:230668
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-5332993
Cellular Component	GO:0005886	plasma membrane	ISO	J:73065
Cellular Component	GO:0005886	plasma membrane	ISO	J:73065
Cellular Component	GO:0005886	plasma membrane	IDA	J:117199
Cellular Component	GO:0005886	plasma membrane	IDA	J:95586
Cellular Component	GO:0005886	plasma membrane	ISO	J:66004
Cellular Component	GO:0005886	plasma membrane	IDA	J:117855
Cellular Component	GO:0005886	plasma membrane	IDA	J:86955
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0042383	sarcolemma	ISO	J:155856
Cellular Component	GO:0042383	sarcolemma	ISO	J:164563
Cellular Component	GO:0042383	sarcolemma	ISO	J:155856
Cellular Component	GO:0042383	sarcolemma	IDA	J:206498
Cellular Component	GO:0042383	sarcolemma	IBA	J:265628
Cellular Component	GO:0042383	sarcolemma	IDA	J:168498
Cellular Component	GO:0042383	sarcolemma	IDA	J:107908
Cellular Component	GO:0042383	sarcolemma	IDA	J:66558
Cellular Component	GO:0042383	sarcolemma	IDA	J:104461
Cellular Component	GO:0042383	sarcolemma	IDA	J:33699
Cellular Component	GO:0042383	sarcolemma	IDA	J:79453
Cellular Component	GO:0042383	sarcolemma	IDA	J:37694
Cellular Component	GO:0030315	T-tubule	ISO	J:155856
Cellular Component	GO:0030315	T-tubule	IDA	J:37694
Cellular Component	GO:0030315	T-tubule	ISO	J:73065
Cellular Component	GO:0030315	T-tubule	IDA	J:104461
Cellular Component	GO:0031982	vesicle	ISO	J:155856
Cellular Component	GO:0030018	Z disc	ISO	J:155856
Biological Process	GO:0007015	actin filament organization	IMP	J:126515
Biological Process	GO:0007015	actin filament organization	IMP	J:126515
Biological Process	GO:0006816	calcium ion transport	IMP	J:168498
Biological Process	GO:0006816	calcium ion transport	IMP	J:168498
Biological Process	GO:0055013	cardiac muscle cell development	IMP	J:150127
Biological Process	GO:0003300	cardiac muscle hypertrophy	IMP	J:138225
Biological Process	GO:0070836	caveola assembly	IBA	J:265628
Biological Process	GO:0070836	caveola assembly	ISO	J:73065
Biological Process	GO:0070836	caveola assembly	IMP	J:130715
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0042632	cholesterol homeostasis	IMP	J:92435
Biological Process	GO:0031122	cytoplasmic microtubule organization	IMP	J:126515
Biological Process	GO:0035995	detection of muscle stretch	IMP	J:217301
Biological Process	GO:0006897	endocytosis	IMP	J:86955
Biological Process	GO:0006897	endocytosis	TAS	J:55894
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:168498
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:86955
Biological Process	GO:0042593	glucose homeostasis	IMP	J:92435
Biological Process	GO:0060347	heart trabecula formation	IMP	J:150127
Biological Process	GO:0000165	MAPK cascade	IMP	J:79453
Biological Process	GO:0000165	MAPK cascade	IMP	J:79453
Biological Process	GO:0031579	membrane raft organization	IMP	J:69965
Biological Process	GO:0031579	membrane raft organization	IMP	J:86955
Biological Process	GO:0046716	muscle cell cellular homeostasis	IEA	J:72247
Biological Process	GO:0007520	myoblast fusion	IMP	J:126515
Biological Process	GO:0014902	myotube differentiation	IMP	J:126515
Biological Process	GO:0014902	myotube differentiation	IMP	J:126515
Biological Process	GO:0014902	myotube differentiation	IMP	J:170588
Biological Process	GO:0051926	negative regulation of calcium ion transport	ISO	J:73065
Biological Process	GO:0051926	negative regulation of calcium ion transport	IMP	J:168498
Biological Process	GO:0010614	negative regulation of cardiac muscle hypertrophy	ISO	J:164563
Biological Process	GO:0010614	negative regulation of cardiac muscle hypertrophy	IMP	J:138225
Biological Process	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development	ISO	J:155856
Biological Process	GO:0045792	negative regulation of cell size	ISO	J:164563
Biological Process	GO:0043407	negative regulation of MAP kinase activity	ISO	J:164563
Biological Process	GO:0043409	negative regulation of MAPK cascade	IMP	J:79453
Biological Process	GO:1900826	negative regulation of membrane depolarization during cardiac muscle cell action potential	IMP	J:217301
Biological Process	GO:0051001	negative regulation of nitric-oxide synthase activity	IMP	J:67174
Biological Process	GO:1901380	negative regulation of potassium ion transmembrane transport	ISO	J:155856
Biological Process	GO:1901017	negative regulation of potassium ion transmembrane transporter activity	ISO	J:155856
Biological Process	GO:0006469	negative regulation of protein kinase activity	IMP	J:86955
Biological Process	GO:0060299	negative regulation of sarcomere organization	ISO	J:164563
Biological Process	GO:0051647	nucleus localization	IMP	J:150127
Biological Process	GO:0007009	plasma membrane organization	IMP	J:79453
Biological Process	GO:0007009	plasma membrane organization	IMP	J:86955
Biological Process	GO:0007009	plasma membrane organization	IMP	J:66558
Biological Process	GO:0001778	plasma membrane repair	IMP	J:150684
Biological Process	GO:2001288	positive regulation of caveolin-mediated endocytosis	ISO	J:155856
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	ISO	J:155856
Biological Process	GO:0031116	positive regulation of microtubule polymerization	ISO	J:155856
Biological Process	GO:0010831	positive regulation of myotube differentiation	IMP	J:126515
Biological Process	GO:0008104	protein localization	IGI	J:95586
Biological Process	GO:0008104	protein localization	IMP	J:104461
Biological Process	GO:0008104	protein localization	IMP	J:69965
Biological Process	GO:0008104	protein localization	IMP	J:79453
Biological Process	GO:0008104	protein localization	IMP	J:86955
Biological Process	GO:0072659	protein localization to plasma membrane	IMP	J:150684
Biological Process	GO:0072659	protein localization to plasma membrane	IMP	J:107908
Biological Process	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis	IMP	J:144177
Biological Process	GO:0090279	regulation of calcium ion import	ISO	J:164563
Biological Process	GO:1901019	regulation of calcium ion transmembrane transporter activity	ISO	J:164563
Biological Process	GO:0051924	regulation of calcium ion transport	IMP	J:109447
Biological Process	GO:0098909	regulation of cardiac muscle cell action potential involved in regulation of contraction	ISO	J:164563
Biological Process	GO:0055117	regulation of cardiac muscle contraction	ISO	J:164563
Biological Process	GO:0051480	regulation of cytosolic calcium ion concentration	IBA	J:265628
Biological Process	GO:0008016	regulation of heart contraction	ISO	J:155856
Biological Process	GO:0002027	regulation of heart rate	ISO	J:164563
Biological Process	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential	ISO	J:164563
Biological Process	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential	IBA	J:265628
Biological Process	GO:0042391	regulation of membrane potential	ISO	J:164563
Biological Process	GO:0042391	regulation of membrane potential	IGI	J:95586
Biological Process	GO:0042391	regulation of membrane potential	IGI	J:95586
Biological Process	GO:0051394	regulation of nerve growth factor receptor activity	ISO	J:73065
Biological Process	GO:1900744	regulation of p38MAPK cascade	IMP	J:170588
Biological Process	GO:0051896	regulation of protein kinase B signaling	IMP	J:170588
Biological Process	GO:0038009	regulation of signal transduction by receptor internalization	ISO	J:73065
Biological Process	GO:0023051	regulation of signaling	IEA	J:72247
Biological Process	GO:0014819	regulation of skeletal muscle contraction	ISO	J:164563
Biological Process	GO:2000649	regulation of sodium ion transmembrane transporter activity	ISO	J:164563
Biological Process	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	IMP	J:170588
Biological Process	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization	ISO	J:164563
Biological Process	GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization	ISO	J:164563
Biological Process	GO:0006641	triglyceride metabolic process	IMP	J:92435
Biological Process	GO:0086005	ventricular cardiac muscle cell action potential	ISO	J:155856