Ppp3r1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Ppp3r1
protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)
MGI:107172

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	IEA	J:72247
Molecular Function	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity	IBA	J:265628
Molecular Function	GO:0016018	cyclosporin A binding	ISO	J:164563
Molecular Function	GO:0019899	enzyme binding	IPI	J:163320
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0019902	phosphatase binding	ISO	J:164563
Molecular Function	GO:0019902	phosphatase binding	IPI	J:257321
Molecular Function	GO:0019902	phosphatase binding	IBA	J:265628
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	ISO	J:155856
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	IMP	J:70266
Molecular Function	GO:0005515	protein binding	IPI	J:163320
Molecular Function	GO:0005515	protein binding	IPI	J:109068
Molecular Function	GO:0005515	protein binding	IPI	J:163320
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:164563
Cellular Component	GO:0005955	calcineurin complex	NAS	J:320122
Cellular Component	GO:0005955	calcineurin complex	IDA	J:257321
Cellular Component	GO:0005955	calcineurin complex	ISO	J:164563
Cellular Component	GO:0005955	calcineurin complex	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	NAS	J:320049
Cellular Component	GO:0005829	cytosol	NAS	J:319677
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-2025936
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:73203
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:73203
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:206458
Cellular Component	GO:0098978	glutamatergic synapse	EXP	J:206458
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:199633
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:199633
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:199633
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:199633
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	IDA	J:199633
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	IMP	J:199633
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0098688	parallel fiber to Purkinje cell synapse	IMP	J:166629
Cellular Component	GO:0098688	parallel fiber to Purkinje cell synapse	IDA	J:166629
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0098794	postsynapse	IDA	J:166629
Cellular Component	GO:0008287	protein serine/threonine phosphatase complex	NAS	J:320049
Cellular Component	GO:0008287	protein serine/threonine phosphatase complex	NAS	J:320050
Cellular Component	GO:0042383	sarcolemma	IDA	J:163320
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IMP	J:73203
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:73203
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:73203
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IMP	J:73203
Cellular Component	GO:0045202	synapse	EXP	J:206458
Cellular Component	GO:0045202	synapse	IDA	J:206458
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	IMP	J:70266
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	IMP	J:70266
Biological Process	GO:0097720	calcineurin-mediated signaling	IBA	J:265628
Biological Process	GO:0033173	calcineurin-NFAT signaling cascade	ISO	J:164563
Biological Process	GO:0033173	calcineurin-NFAT signaling cascade	IGI	J:144171
Biological Process	GO:0033173	calcineurin-NFAT signaling cascade	IGI	J:144171
Biological Process	GO:0001837	epithelial to mesenchymal transition	IMP	J:92515
Biological Process	GO:0007507	heart development	IMP	J:92515
Biological Process	GO:0007507	heart development	IMP	J:92515
Biological Process	GO:0060487	lung epithelial cell differentiation	IMP	J:114501
Biological Process	GO:0022011	myelination in peripheral nervous system	IMP	J:144171
Biological Process	GO:1905949	negative regulation of calcium ion import across plasma membrane	NAS	J:319981
Biological Process	GO:1901386	negative regulation of voltage-gated calcium channel activity	NAS	J:319981
Biological Process	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade	NAS	J:319999
Biological Process	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade	NAS	J:320049
Biological Process	GO:1905665	positive regulation of calcium ion import across plasma membrane	NAS	J:319981
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:1901387	positive regulation of voltage-gated calcium channel activity	NAS	J:319981
Biological Process	GO:0099170	postsynaptic modulation of chemical synaptic transmission	IDA	J:73203
Biological Process	GO:0099170	postsynaptic modulation of chemical synaptic transmission	IMP	J:73203
Biological Process	GO:0099170	postsynaptic modulation of chemical synaptic transmission	IDA	J:166629
Biological Process	GO:0099170	postsynaptic modulation of chemical synaptic transmission	IMP	J:166629
Biological Process	GO:0006470	protein dephosphorylation	ISO	J:155856
Biological Process	GO:0006470	protein dephosphorylation	IBA	J:265628
Biological Process	GO:0006470	protein dephosphorylation	IMP	J:70266
Biological Process	GO:0006606	protein import into nucleus	IMP	J:70266
Biological Process	GO:0034504	protein localization to nucleus	IMP	J:114501
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	IMP	J:73203
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	IMP	J:73203
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	IDA	J:73203
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	IDA	J:73203
Biological Process	GO:0098693	regulation of synaptic vesicle cycle	IMP	J:199633
Biological Process	GO:0098693	regulation of synaptic vesicle cycle	IMP	J:199633
Biological Process	GO:0098693	regulation of synaptic vesicle cycle	IDA	J:199633
Biological Process	GO:0098693	regulation of synaptic vesicle cycle	IDA	J:199633
Biological Process	GO:0098693	regulation of synaptic vesicle cycle	IDA	J:199633
Biological Process	GO:0098693	regulation of synaptic vesicle cycle	IMP	J:199633
Biological Process	GO:0014044	Schwann cell development	IMP	J:144171

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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