GO Annotations Graph

• Symbol: Mttp
• Name: microsomal triglyceride transfer protein
• ID: MGI:106926

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0034185	apolipoprotein binding	ISO	J:155856
Molecular Function	GO:1902388	ceramide 1-phosphate transfer activity	ISO	J:164563
Molecular Function	GO:0120020	cholesterol transfer activity	ISO	J:164563
Molecular Function	GO:0120020	cholesterol transfer activity	IDA	J:296129
Molecular Function	GO:0120020	cholesterol transfer activity	ISO	J:155856
Molecular Function	GO:0008289	lipid binding	IEA	J:72247
Molecular Function	GO:0008289	lipid binding	IEA	J:60000
Molecular Function	GO:0005319	lipid transporter activity	ISO	J:155856
Molecular Function	GO:0005319	lipid transporter activity	IDA	J:78774
Molecular Function	GO:0120019	phosphatidylcholine transfer activity	ISO	J:155856
Molecular Function	GO:0120019	phosphatidylcholine transfer activity	ISO	J:164563
Molecular Function	GO:1904121	phosphatidylethanolamine transfer activity	IDA	J:296129
Molecular Function	GO:1904121	phosphatidylethanolamine transfer activity	ISO	J:164563
Molecular Function	GO:1904121	phosphatidylethanolamine transfer activity	ISO	J:155856
Molecular Function	GO:0120014	phospholipid transfer activity	ISO	J:164563
Molecular Function	GO:0120014	phospholipid transfer activity	IDA	J:306883
Molecular Function	GO:0005548	phospholipid transporter activity	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:306883
Molecular Function	GO:0046982	protein heterodimerization activity	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0140344	triglyceride transfer activity	IDA	J:296130
Molecular Function	GO:0140344	triglyceride transfer activity	ISO	J:164563
Molecular Function	GO:0140344	triglyceride transfer activity	IDA	J:306883
Molecular Function	GO:0140344	triglyceride transfer activity	IDA	J:296129
Molecular Function	GO:0140344	triglyceride transfer activity	ISO	J:155856
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:155856
Cellular Component	GO:0016323	basolateral plasma membrane	IBA	J:265628
Cellular Component	GO:0031526	brush border membrane	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:306883
Cellular Component	GO:0005783	endoplasmic reticulum	IBA	J:265628
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:155856
Cellular Component	GO:0005794	Golgi apparatus	IBA	J:265628
Cellular Component	GO:0031528	microvillus membrane	ISO	J:155856
Cellular Component	GO:0043235	receptor complex	ISO	J:194542
Cellular Component	GO:0005791	rough endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0031982	vesicle	ISO	J:155856
Biological Process	GO:0042632	cholesterol homeostasis	IBA	J:265628
Biological Process	GO:0042632	cholesterol homeostasis	IMP	J:61175
Biological Process	GO:0008203	cholesterol metabolic process	IEA	J:60000
Biological Process	GO:0007623	circadian rhythm	IEP	J:216037
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:61175
Biological Process	GO:0006629	lipid metabolic process	IDA	J:78774
Biological Process	GO:0006869	lipid transport	ISO	J:155856
Biological Process	GO:0042157	lipoprotein metabolic process	ISO	J:155856
Biological Process	GO:0042157	lipoprotein metabolic process	IBA	J:265628
Biological Process	GO:0042157	lipoprotein metabolic process	IMP	J:61175
Biological Process	GO:0042953	lipoprotein transport	IMP	J:61175
Biological Process	GO:0034374	low-density lipoprotein particle remodeling	IDA	J:249196
Biological Process	GO:0015914	phospholipid transport	ISO	J:164563
Biological Process	GO:0034377	plasma lipoprotein particle assembly	ISO	J:164563
Biological Process	GO:0006497	protein lipidation	IDA	J:78774
Biological Process	GO:0009306	protein secretion	ISO	J:164563
Biological Process	GO:0008202	steroid metabolic process	IEA	J:60000
Biological Process	GO:0006641	triglyceride metabolic process	IDA	J:78774
Biological Process	GO:0034197	triglyceride transport	ISO	J:164563