GO Annotations Graph

• Symbol: P2ry1
• Name: purinergic receptor P2Y, G-protein coupled 1
• ID: MGI:105049

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0031686	A1 adenosine receptor binding	ISO	J:155856
Molecular Function	GO:0031686	A1 adenosine receptor binding	IBA	J:265628
Molecular Function	GO:0043531	ADP binding	ISO	J:155856
Molecular Function	GO:0005524	ATP binding	ISO	J:155856
Molecular Function	GO:0005524	ATP binding	ISO	J:164563
Molecular Function	GO:0005524	ATP binding	IBA	J:265628
Molecular Function	GO:0001621	G protein-coupled ADP receptor activity	ISO	J:155856
Molecular Function	GO:0001621	G protein-coupled ADP receptor activity	ISO	J:164563
Molecular Function	GO:0001621	G protein-coupled ADP receptor activity	IBA	J:265628
Molecular Function	GO:0045031	G protein-coupled ATP receptor activity	ISO	J:155856
Molecular Function	GO:0045031	G protein-coupled ATP receptor activity	IBA	J:265628
Molecular Function	GO:0045028	G protein-coupled purinergic nucleotide receptor activity	ISO	J:155856
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:60000
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:72247
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0046982	protein heterodimerization activity	ISO	J:155856
Molecular Function	GO:0097110	scaffold protein binding	ISO	J:155856
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:155856
Cellular Component	GO:0044297	cell body	ISO	J:155856
Cellular Component	GO:0005929	cilium	ISO	J:246963
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:98066
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0048787	presynaptic active zone membrane	ISO	J:155856
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	ISO	J:155856
Biological Process	GO:0097746	blood vessel diameter maintenance	ISO	J:155856
Biological Process	GO:0071407	cellular response to organic cyclic compound	IDA	J:194901
Biological Process	GO:0071415	cellular response to purine-containing compound	ISO	J:164563
Biological Process	GO:0042755	eating behavior	ISO	J:155856
Biological Process	GO:0051649	establishment of localization in cell	IGI	J:118491
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:118491
Biological Process	GO:0051649	establishment of localization in cell	IGI	J:118491
Biological Process	GO:0001973	G protein-coupled adenosine receptor signaling pathway	ISO	J:155856
Biological Process	GO:0035589	G protein-coupled purinergic nucleotide receptor signaling pathway	ISO	J:155856
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	ISO	J:155856
Biological Process	GO:0008347	glial cell migration	ISO	J:155856
Biological Process	GO:0006811	monoatomic ion transport	IGI	J:118491
Biological Process	GO:0006811	monoatomic ion transport	IGI	J:118491
Biological Process	GO:0006811	monoatomic ion transport	IMP	J:118491
Biological Process	GO:0006811	monoatomic ion transport	IGI	J:118491
Biological Process	GO:0006811	monoatomic ion transport	IGI	J:118491
Biological Process	GO:0006811	monoatomic ion transport	IMP	J:118491
Biological Process	GO:0051100	negative regulation of binding	ISO	J:155856
Biological Process	GO:0010700	negative regulation of norepinephrine secretion	ISO	J:155856
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	IBA	J:265628
Biological Process	GO:0030168	platelet activation	IEA	J:72247
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	ISO	J:155856
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	ISO	J:155856
Biological Process	GO:0046887	positive regulation of hormone secretion	ISO	J:155856
Biological Process	GO:0032962	positive regulation of inositol trisphosphate biosynthetic process	ISO	J:155856
Biological Process	GO:0043270	positive regulation of monoatomic ion transport	IGI	J:118491
Biological Process	GO:0043270	positive regulation of monoatomic ion transport	IGI	J:118491
Biological Process	GO:0043270	positive regulation of monoatomic ion transport	IMP	J:118491
Biological Process	GO:0060406	positive regulation of penile erection	ISO	J:155856
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0072659	protein localization to plasma membrane	ISO	J:155856
Biological Process	GO:0008360	regulation of cell shape	ISO	J:164563
Biological Process	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	ISO	J:155856
Biological Process	GO:0010469	regulation of signaling receptor activity	ISO	J:155856
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	ISO	J:155856
Biological Process	GO:0090075	relaxation of muscle	IEA	J:72247
Biological Process	GO:0009612	response to mechanical stimulus	ISO	J:155856
Biological Process	GO:0019233	sensory perception of pain	ISO	J:155856
Biological Process	GO:0007165	signal transduction	IEA	J:60000
Biological Process	GO:0023019	signal transduction involved in regulation of gene expression	ISO	J:155856