GO Annotations Graph

• Symbol: Gpc3
• Name: glypican 3
• ID: MGI:104903

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0030414	peptidase inhibitor activity	IEA	J:60000
Molecular Function	GO:0060422	peptidyl-dipeptidase inhibitor activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:135168
Molecular Function	GO:0005515	protein binding	IPI	J:134067
Cellular Component	GO:0009986	cell surface	IBA	J:265628
Cellular Component	GO:0062023	collagen-containing extracellular matrix	IEA	J:72247
Cellular Component	GO:0005796	Golgi lumen	TAS	Reactome:R-MMU-2024090
Cellular Component	GO:0005764	lysosome	IDA	J:135168
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISS	J:28429
Cellular Component	GO:0005886	plasma membrane	IMP	J:135168
Cellular Component	GO:0005886	plasma membrane	IDA	J:134067
Biological Process	GO:0009887	animal organ morphogenesis	IMP	J:51288
Biological Process	GO:0009948	anterior/posterior axis specification	IGI	J:64330
Biological Process	GO:0010171	body morphogenesis	IMP	J:135168
Biological Process	GO:0030282	bone mineralization	IMP	J:104555
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	IGI	J:99651
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	IGI	J:99651
Biological Process	GO:0060070	canonical Wnt signaling pathway	IMP	J:96157
Biological Process	GO:0016477	cell migration	IBA	J:265628
Biological Process	GO:0072111	cell proliferation involved in kidney development	IMP	J:67732
Biological Process	GO:0072203	cell proliferation involved in metanephros development	IMP	J:73877
Biological Process	GO:0060976	coronary vasculature development	IMP	J:154375
Biological Process	GO:0060976	coronary vasculature development	IMP	J:154375
Biological Process	GO:0035116	embryonic hindlimb morphogenesis	IGI	J:64330
Biological Process	GO:0050673	epithelial cell proliferation	IMP	J:73877
Biological Process	GO:0050673	epithelial cell proliferation	IMP	J:73877
Biological Process	GO:0040007	growth	IMP	J:96157
Biological Process	GO:0001822	kidney development	IMP	J:73877
Biological Process	GO:0030324	lung development	IMP	J:73877
Biological Process	GO:0072138	mesenchymal cell proliferation involved in ureteric bud development	IMP	J:99651
Biological Process	GO:0072180	mesonephric duct morphogenesis	IMP	J:67732
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	ISO	J:73065
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	IMP	J:96157
Biological Process	GO:0008285	negative regulation of cell population proliferation	IGI	J:99651
Biological Process	GO:0008285	negative regulation of cell population proliferation	IGI	J:99651
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	IMP	J:73877
Biological Process	GO:0045926	negative regulation of growth	IMP	J:96157
Biological Process	GO:0045926	negative regulation of growth	IMP	J:75054
Biological Process	GO:0010466	negative regulation of peptidase activity	IEA	J:60000
Biological Process	GO:0045879	negative regulation of smoothened signaling pathway	IGI	J:157333
Biological Process	GO:0045879	negative regulation of smoothened signaling pathway	IMP	J:135168
Biological Process	GO:0030316	osteoclast differentiation	IMP	J:104555
Biological Process	GO:0030513	positive regulation of BMP signaling pathway	IMP	J:99651
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	IBA	J:265628
Biological Process	GO:0045807	positive regulation of endocytosis	IDA	J:135168
Biological Process	GO:0046326	positive regulation of glucose import	IDA	J:134067
Biological Process	GO:0045732	positive regulation of protein catabolic process	IDA	J:135168
Biological Process	GO:0045880	positive regulation of smoothened signaling pathway	IMP	J:154375
Biological Process	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway	IMP	J:96157
Biological Process	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway	ISO	J:73065
Biological Process	GO:0060828	regulation of canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0040008	regulation of growth	IMP	J:73877
Biological Process	GO:0040008	regulation of growth	IGI	J:157333
Biological Process	GO:2000050	regulation of non-canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:1905475	regulation of protein localization to membrane	IBA	J:265628
Biological Process	GO:0009966	regulation of signal transduction	IEA	J:72247
Biological Process	GO:0009617	response to bacterium	IEP	J:190322
Biological Process	GO:0007224	smoothened signaling pathway	IMP	J:154375
Biological Process	GO:0060071	Wnt signaling pathway, planar cell polarity pathway	IMP	J:96157