GO Annotations Graph

• Symbol: Osm
• Name: oncostatin M
• ID: MGI:104749

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005125	cytokine activity	ISO	J:164563
Molecular Function	GO:0005125	cytokine activity	IBA	J:265628
Molecular Function	GO:0005125	cytokine activity	IDA	J:88684
Molecular Function	GO:0008083	growth factor activity	ISO	J:164563
Molecular Function	GO:0005147	oncostatin-M receptor binding	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	IEA	J:72247
Cellular Component	GO:0005615	extracellular space	IEA	J:60000
Biological Process	GO:0048266	behavioral response to pain	IMP	J:97000
Biological Process	GO:0006955	immune response	IEA	J:72247
Biological Process	GO:0140013	meiotic nuclear division	IDA	J:67053
Biological Process	GO:0046888	negative regulation of hormone secretion	ISO	J:73065
Biological Process	GO:0045835	negative regulation of meiotic nuclear division	IDA	J:67053
Biological Process	GO:0038165	oncostatin-M-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0007422	peripheral nervous system development	IMP	J:97000
Biological Process	GO:2001235	positive regulation of apoptotic signaling pathway	IDA	J:88684
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0050729	positive regulation of inflammatory response	ISO	J:164563
Biological Process	GO:0032740	positive regulation of interleukin-17 production	ISO	J:164563
Biological Process	GO:0043410	positive regulation of MAPK cascade	ISO	J:73065
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	ISO	J:73065
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	ISO	J:73065
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	IDA	J:206059
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	ISO	J:164563
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:73065
Biological Process	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	ISO	J:164563
Biological Process	GO:0040008	regulation of growth	IEA	J:60000
Biological Process	GO:0009408	response to heat	IMP	J:97000
Biological Process	GO:0007260	tyrosine phosphorylation of STAT protein	IDA	J:88684