GO Annotations Graph

• Symbol: Lilrb4a
• Name: leukocyte immunoglobulin-like receptor, subfamily B, member 4A
• ID: MGI:102701

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0034185	apolipoprotein binding	ISO	J:164563
Molecular Function	GO:0001968	fibronectin binding	IDA	J:314650
Molecular Function	GO:0001968	fibronectin binding	ISO	J:164563
Molecular Function	GO:0032396	inhibitory MHC class I receptor activity	IBA	J:265628
Molecular Function	GO:0005178	integrin binding	IDA	J:296155
Molecular Function	GO:0019902	phosphatase binding	IPI	J:314642
Molecular Function	GO:0019903	protein phosphatase binding	ISO	J:164563
Molecular Function	GO:0019903	protein phosphatase binding	IPI	J:314643
Molecular Function	GO:0030547	signaling receptor inhibitor activity	ISO	J:164563
Molecular Function	GO:0030293	transmembrane receptor protein tyrosine kinase inhibitor activity	ISO	J:164563
Cellular Component	GO:0009986	cell surface	IDA	J:64504
Cellular Component	GO:0009986	cell surface	IDA	J:296155
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0009986	cell surface	IDA	J:37741
Cellular Component	GO:0009986	cell surface	IDA	J:314847
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:119423
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:159431
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:129969
Biological Process	GO:0007596	blood coagulation	IMP	J:119423
Biological Process	GO:0035739	CD4-positive, alpha-beta T cell proliferation	IMP	J:141234
Biological Process	GO:0035740	CD8-positive, alpha-beta T cell proliferation	IMP	J:141234
Biological Process	GO:0071222	cellular response to lipopolysaccharide	IMP	J:119423
Biological Process	GO:0032602	chemokine production	IMP	J:97785
Biological Process	GO:0001816	cytokine production	IMP	J:97785
Biological Process	GO:0019221	cytokine-mediated signaling pathway	IBA	J:265628
Biological Process	GO:0002774	Fc receptor mediated inhibitory signaling pathway	ISO	J:164563
Biological Process	GO:0006954	inflammatory response	IMP	J:129969
Biological Process	GO:0002437	inflammatory response to antigenic stimulus	IMP	J:159431
Biological Process	GO:0046007	negative regulation of activated T cell proliferation	ISO	J:164563
Biological Process	GO:0032682	negative regulation of chemokine production	ISO	J:164563
Biological Process	GO:1900016	negative regulation of cytokine production involved in inflammatory response	ISO	J:164563
Biological Process	GO:0045584	negative regulation of cytotoxic T cell differentiation	ISO	J:164563
Biological Process	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0002638	negative regulation of immunoglobulin production	IMP	J:313953
Biological Process	GO:0032691	negative regulation of interleukin-1 beta production	ISO	J:164563
Biological Process	GO:0032693	negative regulation of interleukin-10 production	ISO	J:164563
Biological Process	GO:0032703	negative regulation of interleukin-2 production	ISO	J:164563
Biological Process	GO:0032714	negative regulation of interleukin-5 production	ISO	J:164563
Biological Process	GO:0032715	negative regulation of interleukin-6 production	ISO	J:164563
Biological Process	GO:0071659	negative regulation of IP-10 production	ISO	J:164563
Biological Process	GO:0043409	negative regulation of MAPK cascade	ISO	J:164563
Biological Process	GO:0033004	negative regulation of mast cell activation	IMP	J:84936
Biological Process	GO:0033007	negative regulation of mast cell activation involved in immune response	IMP	J:70491
Biological Process	GO:0033007	negative regulation of mast cell activation involved in immune response	IPI	J:296155
Biological Process	GO:0033007	negative regulation of mast cell activation involved in immune response	IDA	J:314643
Biological Process	GO:0033007	negative regulation of mast cell activation involved in immune response	IDA	J:37741
Biological Process	GO:1902894	negative regulation of miRNA transcription	ISO	J:164563
Biological Process	GO:0150102	negative regulation of monocyte activation	IDA	J:314650
Biological Process	GO:0150102	negative regulation of monocyte activation	ISO	J:164563
Biological Process	GO:0032815	negative regulation of natural killer cell activation	IDA	J:314847
Biological Process	GO:0045671	negative regulation of osteoclast differentiation	ISO	J:164563
Biological Process	GO:1900099	negative regulation of plasma cell differentiation	IMP	J:313953
Biological Process	GO:1900181	negative regulation of protein localization to nucleus	ISO	J:164563
Biological Process	GO:0061099	negative regulation of protein tyrosine kinase activity	ISO	J:164563
Biological Process	GO:2000272	negative regulation of signaling receptor activity	ISO	J:164563
Biological Process	GO:2000524	negative regulation of T cell costimulation	ISO	J:164563
Biological Process	GO:0002725	negative regulation of T cell cytokine production	ISO	J:164563
Biological Process	GO:0042130	negative regulation of T cell proliferation	ISO	J:164563
Biological Process	GO:0050860	negative regulation of T cell receptor signaling pathway	ISO	J:164563
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	ISO	J:164563
Biological Process	GO:0032689	negative regulation of type II interferon production	ISO	J:164563
Biological Process	GO:0001780	neutrophil homeostasis	IMP	J:97785
Biological Process	GO:0043378	positive regulation of CD8-positive, alpha-beta T cell differentiation	ISO	J:164563
Biological Process	GO:0045591	positive regulation of regulatory T cell differentiation	ISO	J:164563
Biological Process	GO:0002669	positive regulation of T cell anergy	ISO	J:164563
Biological Process	GO:0031623	receptor internalization	ISO	J:164563
Biological Process	GO:0009991	response to extracellular stimulus	IMP	J:197195
Biological Process	GO:0032496	response to lipopolysaccharide	IMP	J:197195
Biological Process	GO:0032496	response to lipopolysaccharide	IMP	J:97785
Biological Process	GO:0032496	response to lipopolysaccharide	IMP	J:119423
Biological Process	GO:0009624	response to nematode	IMP	J:129969
Biological Process	GO:0051707	response to other organism	IMP	J:259624
Biological Process	GO:0009611	response to wounding	IMP	J:119423
Biological Process	GO:0002507	tolerance induction	ISO	J:164563
Biological Process	GO:0042092	type 2 immune response	IMP	J:159431