About   Help   FAQ
tk Gene Detail
Summary
  • Symbol
    tk
  • Name
    tail-kinks
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:98760
    NCBI Gene: 21874
  • Alliance
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 9, Syntenic
  • Mapping Data
    31 experiments
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    3 images
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mutations in this gene result in abnormal vertebrae development, with a shortened and kinked tail especially noticeable.
Sequences &
Gene Models
less
Other
Accession IDs
less
MGD-MRK-15120
References
more
  • Summaries
    All 17
    Phenotypes 4
  • Earliest
    J:14982 Gruneberg H, Genetical studies on the skeleton of the mouse. XVI. Tail-kinks. J Genet. 1955;53:536-50
  • Latest
    J:121463 Kaja S, et al., Redundancy of Cav2.1 channel accessory subunits in transmitter release at the mouse neuromuscular junction. Brain Res. 2007 Apr 27;1143:92-101

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Copyright, and Privacy Statement
Send questions and comments to User Support.
last database update
01/17/2023
MGI 6.22
The Jackson Laboratory