Serpina3kr Gene Detail

Summary

• Symbol
  Serpina3kr
• Name
  serine (or cysteine) peptidase inhibitor, clade A, member 3K regulator
• Synonyms
  Spi2r, Spi-2r

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:98379
  NCBI Gene: 110121
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 12, Syntenic
• Mapping Data
  4 experiments

Mutations,
Alleles, and
Phenotypes

This locus encodes a cis-acting transcription regulator that controls RNA transcripts of its structural gene in liver. In some strains, including DBA/2 and BALB/c, these transcripts are synthesized constitutively; in others, including C57BL/6 and C3H/He they are induced by inflammation.

Sequences &
Gene Models

• NCBI Gene
  110121

Other
Accession IDs

MGD-MRK-14523, MGD-MRK-14528

References

• Summaries
  All 6
• Earliest
  J:8404 Hill RE, et al., A genetic locus closely linked to a protease inhibitor gene complex controls the level of multiple RNA transcripts. Mol Cell Biol. 1985 Aug;5(8):2114-22
• Latest
  J:53210 Libert C, et al., Identification of a locus on distal mouse chromosome 12 that controls resistance to tumor necrosis factor-induced lethal shock. Genomics. 1999 Feb 1;55(3):284-9