Sgp1 QTL Detail

Summary

• Symbol
  Sgp1
• Name
  serum gp70 production 1
• Synonyms
  Sgp-1

• Feature Type
  QTL
• IDs
  MGI:98290
  NCBI Gene: 109941

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 17, cM position of peak correlated region/marker: Syntenic
• Mapping Data
  1 experiment

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from 1 allele in 1 genetic background
  1 phenotype reference
  

• All Mutations and Alleles
  2
• QTL
  2
• Find Mice (IMSR)
  0 strains or lines available

Sgp1 and Sgp2 control serum level of gp70. Sgp1 allele a, in H2d mice, determines high serum gp70; allele b, in mice with most H2 haplotypes, determines low serum gp70 and increased gp70 response to LPS. The c allele, in H2s mice, determines low gp70 andlack of LPS response.

Sequences &
Gene Models

• NCBI Gene
  109941

Other
Accession IDs

MGD-MRK-14387, MGD-MRK-14389

References

• Summaries
  All 3

  Phenotypes 1
• Earliest
  J:7046 Maruyama N, et al., H-2-linked regulation of serum gp70 production in mice. Immunogenetics. 1983;17(5):507-21