Pepc Gene Detail

Summary

• Symbol
  Pepc
• Name
  peptidase C
• Synonyms
  Dip-1, Pep-3, Pep3

• Feature Type
  unclassified gene
• IDs
  MGI:97541
  NCBI Gene: 109616
• Alliance
  genome feature page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 1, Syntenic
• Mapping Data
  144 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from 5 alleles in 1 genetic background
  5 phenotypes from multigenic genotypes
  111 phenotype references
  

• All Mutations and Alleles
  8
• Chemically induced (ENU)
  4
• Chemically induced (other)
  1
• Find Mice (IMSR)
  17 strains or lines available

Electrophoretic variants of red blood cell PEPC are: C57BL/6 has a slow anodal band (a allele); CBA/J and A/He, a faster band (b allele); NZB, ST/b and RIIIS/J, an even faster band (c allele). Heterozygotes have both bands. Mice homozygous for ENU or procarbazine induced null alleles are viable.

Sequences &
Gene Models

• NCBI Gene
  109616

Other
Accession IDs

MGD-MRK-13233, MGD-MRK-13238, MGD-MRK-8850

References

• Summaries
  All 222

  Phenotypes 111
• Earliest
  J:5133 Lewis WH, et al., Electrophoretic heterogeneity of mouse erythrocyte peptidases. Biochem Genet. 1969 Oct;3(5):493-8
• Latest
  J:387648 Perkins B, et al., Ets1 represses Blimp1 to promote germinal center T follicular helper cell differentiation during viral infection. J Immunol. 2026 May 14;215(5)