Melc Gene Detail

Summary

• Symbol
  Melc
• Name
  melanocyte population size

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:96962
  NCBI Gene: 104390
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome Unknown

Mutations,
Alleles, and
Phenotypes

From birth to 3-4 days of age, the number of melanocytes positive for dopa reaction in dorsal epidermis increases, then decreases. In contrast, the number of melanoblasts plus melanocytes is constant, then decreases. This developmental pattern is similarin C57BL/10J and C3H/He mice, but cell population sizes differ. Two semidominant genes are indicated: Melc controlling melanocyte cell number and Melb controlling melanoblast plus melanocyte number.

Sequences &
Gene Models

• NCBI Gene
  104390

Other
Accession IDs

MGD-MRK-12192

References

• Summaries
  All 2
• Earliest
  J:6924 Hirobe T, Genes involved in regulating the melanocyte and melanoblast-melanocyte populations in the epidermis of newborn mouse skin. J Exp Zool. 1982 Nov 1;223(3):257-64