Map1 Gene Detail

Summary

• Symbol
  Map1
• Name
  mannosidase processing 1
• Synonyms
  Map-1

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:96917
  NCBI Gene: 109953
• Alliance
  genome feature page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 5, Syntenic
• Mapping Data
  2 experiments

Mutations,
Alleles, and
Phenotypes

This liver-expressed gene appears to control posttranslational sialylation of an acid lysosomal alpha-mannosidase. Electrophoretic alleles are: the dominant b allele determining a fast anodally migrating band in C57BL/6J; and the h allele determining a slower band in CBA/J, C3H/HeJ and AKR/J.

Sequences &
Gene Models

• NCBI Gene
  109953

Other
Accession IDs

MGD-MRK-12113, MGD-MRK-12115

References

• Summaries
  All 6
• Earliest
  J:5798 Dizik M, et al., A gene apparently determining the extent of sialylation of lysosomal alpha-mannosidase in mouse liver. Biochem Genet. 1977 Feb;15(1-2):31-46
• Latest
  J:390258 Dalal V, et al., Transcription factor 21 deletion from podocyte precursors as a model for congenital nephrotic syndrome. Am J Physiol Renal Physiol. 2026 Jun 1;330(6):F746-F760