Int41 Gene Detail

Summary

• Symbol
  Int41
• Name
  mammary tumor integration site 41
• Synonyms
  Int-41

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:96577
  NCBI Gene: 110307
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 6, Syntenic
• Mapping Data
  1 experiment

Strain
Comparison

• RFLP
  1

Mutations,
Alleles, and
Phenotypes

BALB/cf/Cd inbreds have a high incidence of kidney adenocarcinomas. The Int41 locus, identified as interrupted by integration of exogenous MMTV in a BALB/c mammary tumor, is implicated in neoplastic changes in several organs.

Sequences &
Gene Models

• NCBI Gene
  110307

Molecular
Reagents

• All nucleic 6

  Genomic 6

Other
Accession IDs

MGD-MRK-11423, MGD-MRK-11429

References

• Summaries
  All 6
• Earliest
  J:8229 Garcia M, et al., A new site of integration for mouse mammary tumor virus proviral DNA common to BALB/cf(C3H) mammary and kidney adenocarcinomas. EMBO J. 1986 Jan;5(1):127-34
• Latest
  J:10578 de Lapeyriere O, et al., Structure, chromosome mapping and expression of the murine Fgf-6 gene. Oncogene. 1990 Jun;5(6):823-31