Ezg Gene Detail

Summary

• Symbol
  Ezg
• Name
  extent of zona glomerulosa

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:95472
  NCBI Gene: 104375
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome Unknown

Mutations,
Alleles, and
Phenotypes

The dominant allele of Ezg determines a wide, well defined adrenal zona glomerulosa in CBA and A/Cam; the recessive allele, a narrow poorly defined zona in Peru and SF/Cam. Sodium deficiency causes glomerular hypertrophy in CBA, but not Peru mice, although aldosterone secretion rate is the same.

Sequences &
Gene Models

• NCBI Gene
  104375

Other
Accession IDs

MGD-MRK-9692

References

• Summaries
  All 3
• Earliest
  J:5117 Shire JG, A strain difference in the adrenal zona glomerulosa determined by one gene-locus. Endocrinology. 1969 Sep;85(3):415-22
• Latest
  J:5259 Stewart J, et al., Aldosterone production and the zona glomerulosa: a genetic study. Endocrinology. 1972 Apr;90(4):968-72