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Cat2 Gene Detail
Summary
  • Symbol
    Cat2
  • Name
    dominant cataract 2
  • Synonyms
    Cat-2, nuclear and zonular cataract, Nzc, Rop, Scat
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:88272
    NCBI Gene: 111335
  • Alliance
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 1, Syntenic
  • Mapping Data
    9 experiments
Human Diseases
more
  • Diseases
    1 with Cat2 mouse models

Human Disease Mouse Models
      
IDs
View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice heterozygous for an ENU-induced allele exhibit cataracts.
Expression
less
  • Other Vertebrate Links
    Xenbase cat2
Sequences &
Gene Models
less
Other
Accession IDs
less
MGD-MRK-12908, MGD-MRK-12957, MGD-MRK-14009, MGD-MRK-14300, MGD-MRK-1768, MGD-MRK-1770, MGD-MRK-9358
References
more
  • Summaries
    All 29
    Diseases 1
    Phenotypes 3
  • Earliest
    J:6481 Oda S, et al., Impaired development of lens fibers in genetic microphthalmia, eye lens obsolescence, Elo, of the mouse. Exp Eye Res. 1980 Dec;31(6):673-81
  • Latest
    J:90087 Graw J, et al., Genetic and allelic heterogeneity of Cryg mutations in eight distinct forms of dominant cataract in the mouse. Invest Ophthalmol Vis Sci. 2004 Apr;45(4):1202-13

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
11/28/2023
MGI 6.22
The Jackson Laboratory