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Asc1 Gene Detail
Summary
  • Symbol
    Asc1
  • Name
    anterior suture cataract 1
  • Synonyms
    Asc-1
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:88079
    NCBI Gene: 104385
  • Alliance
    gene page
Location &
Maps
less
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome Unknown
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mutation of this gene causes anterior polar opacity of the lens with a lens suture anomaly and a pupillary membrane abnormality in the iris.
Sequences &
Gene Models
less
Other
Accession IDs
less
MGD-MRK-1409, MGD-MRK-1411
References
more
  • Summaries
    All 4
    Phenotypes 1
  • Earliest
    J:9528 Kratochvilova J, et al., Phenotypic characterization and genetic analysis of twenty dominant cataract mutations detected in offspring of irradiated male mice. Genet Res. 1988 Oct;52(2):125-34
  • Latest
    J:257414 Sason H, et al., Asc-1 Transporter Regulation of Synaptic Activity via the Tonic Release of d-Serine in the Forebrain. Cereb Cortex. 2017 Feb 1;27(2):1573-1587
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory