Aecp QTL Detail

Summary

• Symbol
  Aecp
• Name
  vitamin A enhanced cleft palate
• Synonyms
  Acp

• Feature Type
  QTL
• IDs
  MGI:87949
  NCBI Gene: 110202

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 17, cM position of peak correlated region/marker: Syntenic
• Mapping Data
  2 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotype references
  

• All Mutations and Alleles
  1
• Find Mice (IMSR)
  0 strains or lines available

Dexamethasone given during pregnancy can induce cleft palate in mouse embryos. The Aecp haplotype increases the susceptibility to the effects of dexamethasone.

Sequences &
Gene Models

• NCBI Gene
  110202

Other
Accession IDs

MGD-MRK-1170

References

• Summaries
  All 5

  Phenotypes 2
• Earliest
  J:103482 Tyan ML, Vitamin A-enhanced cleft palate susceptibility associated with H-2. J Immunogenet. 1987 Aug-Oct;14(4-5):239-45
• Latest
  J:103481 Tyan ML, Effects of H-2 and dietary vitamin A on the frequency of dorsoventral vaginal septum. Proc Soc Exp Biol Med. 1993 Jun;203(2):175-8