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Ad Gene Detail
Summary
  • Symbol
    Ad
  • Name
    adult obesity and diabetes
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:87915
    NCBI Gene: 104253
  • Alliance
Location &
Maps
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  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 7, Syntenic
  • Mapping Data
    1 experiment
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous and heterozygous mice display adiposity by 4 to 6 months of age resulting from larger fat cell size. Obese mice are hyperinsulinemic but have normal blood glucose levels.
Sequences &
Gene Models
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Other
Accession IDs
less
MGD-MRK-1103
References
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  • Summaries
    All 6
    Phenotypes 4
  • Earliest
    J:6095 Trayhurn P, et al., Studies on the body composition, fat distribution and fat cell size and number of 'Ad', a new obese mutant mouse. Br J Nutr. 1979 Jan;41(1):211-21
  • Latest
    J:56197 Schalling M, et al., Genes involved in animal models of obesity and anorexia. J Intern Med. 1999 Jun;245(6):613-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory