Tg(CDHR3*)17577Scull
Transgene Detail

Summary

• Symbol: Tg(CDHR3*)17577Scull
• Name: transgene insertion 17577, Margaret Scull
• MGI ID: MGI:8292139
• Transgene: Tg(CDHR3*)17577Scull Location: unknown
• Alliance: Tg(CDHR3*)17577Scull page

Transgene origin

• Strain of Origin: C57BL/6NTac

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Mutation details:

  The transgene expresses a modified CDHR3 (point mutation, C529Y (rs6967330, TGT->TAT)) gene expressed from the human CDHR3 promoter that increases cell surface expression of CDHR3. (J:374947)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:374947 Goldstein ME, et al., Human Stimulator of Interferon Genes Promotes Rhinovirus C Replication in Mouse Cells In Vitro and In Vivo. Viruses. 2024 Aug 10;16(8)
• All: 1 reference(s)