Rr695558 Other Genome Feature Detail

Summary

• Symbol
  Rr695558
• Name
  regulatory region r695558
• Synonyms
  Prrx1 R1A

• Feature Type
  enhancer
• IDs
  MGI:8209691
• Cluster Members
  Rr422077, Rr422078 (2 members)
• Alliance
  genome feature page
• Regulates expression of
  Prrx1 (1 regulated gene)

Location &
Maps

• Sequence Map
  Chr1:163152908-163183319 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI
• chr1:163152908-163183319 (GRCm39)

• Genetic Map
  Chromosome 1, Syntenic

Strain
Comparison

• SNPs within 2kb
  948 from dbSNP Build 142

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotype references
  

• All Mutations and Alleles
  2
• Endonuclease-mediated
  2
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 3

  Phenotypes 2
• Earliest
  J:362588 Bosada FM, et al., A Variant Noncoding Region Regulates Prrx1 and Predisposes to Atrial Arrhythmias. Circ Res. 2021 Jul 23;129(3):420-434
• Latest
  J:360861 Bosada FM, et al., An atrial fibrillation-associated regulatory region modulates cardiac Tbx5 levels and arrhythmia susceptibility. Elife. 2023 Jan 30;12

Rr695558 regulates expression of:

Feature	Feature Type	Location	Reference
Prrx1, paired related homeobox 1	protein coding gene	Chr1:163072688-163141279 (-)	J:362588

Rr695558 Cluster contains:

More Data for these features

Member	Feature Type	Location
Rr422077, regulatory region 422077	enhancer	Chr1:163165399-163165830
Rr422078, regulatory region 422078	enhancer	Chr1:163166023-163166974