Rr625 Other Genome Feature Detail

Summary

• Symbol
  Rr625
• Name
  regulatory region 625
• Synonyms
  DNS

• Feature Type
  enhancer
• IDs
  MGI:8170739
• Cluster Members
  Rr553327, Rr553328 (2 members)
• Regulates expression of
  Notch1 (1 regulated gene)

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.
• chr2:26403331-26403981 (GRCm39)

• Genetic Map
  Chromosome 2, Syntenic

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype reference
  

• All Mutations and Alleles
  3
• Endonuclease-mediated
  2
• Targeted
  1
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 2

  Phenotypes 1
• Earliest
  J:362109 Kashiwagi M, et al., A double-negative thymocyte-specific enhancer augments Notch1 signaling to direct early T cell progenitor expansion, lineage restriction and beta-selection. Nat Immunol. 2022 Nov;23(11):1628-1643

Rr625 regulates expression of:

Feature	Feature Type	Location	Reference
Notch1, notch 1	protein coding gene	Chr2:26347914-26393834 (-)	J:362109

Rr625 Cluster contains:

More Data for these features

Member	Feature Type	Location
Rr553327, regulatory region 553327	enhancer	Chr2:26403161-26403815 (.)
Rr553328, regulatory region 553328	enhancer	Chr2:26403943-26404158 (.)