Rr446850 Other Genome Feature Detail

Summary

• Symbol
  Rr446850
• Name
  regulatory region 446850
• Synonyms
  Tcf7 EPE3

• Feature Type
  enhancer
• IDs
  MGI:7908982
• Regulates expression of
  Tcf7 (1 regulated gene)

Location &
Maps

• Sequence Map
  Chr11:52204331-52205232 bp

  From Ensembl Reg annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 11, Syntenic
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  108 from dbSNP Build 142

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotype references
  

• All Mutations and Alleles
  5
• Endonuclease-mediated
  5
• Genomic Mutations
  2 involving Rr446850
• Find Mice (IMSR)
  0 strains or lines available

Sequences &
Gene Models

• All Sequences
  1

Representative Sequences			Length	Strain/Species
genomic	ENSMUSR11_BDCPQ	Ensembl | MGI Sequence Detail	902	Not Applicable

Other Database
Links

Ensembl Regulatory Feature

ENSMUSR11_BDCPQ

References

• Summaries
  All 3

  Phenotypes 2
• Earliest
  J:337301 Harly C, et al., A Shared Regulatory Element Controls the Initiation of Tcf7 Expression During Early T Cell and Innate Lymphoid Cell Developments. Front Immunol. 2020;11:470
• Latest
  J:372296 Verma A, et al., TCF1 dosage determines cell fate during T cell development. Sci Adv. 2024 Nov 29;10(48):eado5982

Rr446850 regulates expression of:

Feature	Feature Type	Location	Reference
Tcf7, transcription factor 7, T cell specific	protein coding gene	Chr11:52143198-52174158 (-)	J:337301
Tcf7, transcription factor 7, T cell specific	protein coding gene	Chr11:52143198-52174158 (-)	J:372296