Rr590 Other Genome Feature Detail

Summary

• Symbol
  Rr590
• Name
  regulatory region 590
• Synonyms
  M21

• Feature Type
  enhancer
• IDs
  MGI:7790907
• Regulates expression of
  Cyp27b1 (1 regulated gene)

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.
• chr10:126869870-126874496 (GRCm39)

• Genetic Map
  Chromosome 10, Syntenic

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  3 phenotype references
  

• All Mutations and Alleles
  3
• Endonuclease-mediated
  3
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 5

  Phenotypes 3
• Earliest
  J:246808 Meyer MB, et al., A kidney-specific genetic control module in mice governs endocrine regulation of the cytochrome P450 gene Cyp27b1 essential for vitamin D3 activation. J Biol Chem. 2017 Oct 20;292(42):17541-17558
• Latest
  J:359655 Meyer MB, et al., In Vivo Contribution of Cyp24a1 Promoter Vitamin D Response Elements. Endocrinology. 2024 Sep 26;165(11)

Rr590 regulates expression of:

Feature	Feature Type	Location	Reference
Cyp27b1, cytochrome P450, family 27, subfamily b, polypeptide 1	protein coding gene	Chr10:126884119-126888875 (+)	J:281102