Rr501 Other Genome Feature Detail

Summary

• Symbol
  Rr501
• Name
  regulatory region 501
• Synonyms
  Epas1 mENH5

• Feature Type
  enhancer
• IDs
  MGI:7705862
• Regulates expression of
  Epas1 (1 regulated gene)

Location &
Maps

• Sequence Map
  Chr17:87109165-87110166 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI
• J:351049 coordinates: chr17:86801737-86802738 (mm10) chr17:87109165-87110166 (GRCm39)

• Genetic Map
  Chromosome 17, Syntenic

Strain
Comparison

• SNPs within 2kb
  138 from dbSNP Build 142

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Endonuclease-mediated
  1
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 2

  Phenotypes 1
• Earliest
  J:351049 Gray OA, et al., A pleiotropic hypoxia-sensitive EPAS1 enhancer is disrupted by adaptive alleles in Tibetans. Sci Adv. 2022 Nov 25;8(47):eade1942

Rr501 regulates expression of:

Feature	Feature Type	Location	Reference
Epas1, endothelial PAS domain protein 1	protein coding gene	Chr17:87061292-87140838 (+)	J:351049