Rr496 Other Genome Feature Detail

Summary

• Symbol
  Rr496
• Name
  regulatory region 496
• Synonyms
  Pitx1-RA2

• Feature Type
  promoter
• IDs
  MGI:7666523
• Regulates expression of
  Pitx1 (1 regulated gene)

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 13, Syntenic

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotype references
  

• All Mutations and Alleles
  2
• Endonuclease-mediated
  2
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 3

  Phenotypes 2
• Earliest
  J:268374 Kragesteen BK, et al., Dynamic 3D chromatin architecture contributes to enhancer specificity and limb morphogenesis. Nat Genet. 2018 Oct;50(10):1463-1473
• Latest
  J:317420 Rouco R, et al., Cell-specific alterations in Pitx1 regulatory landscape activation caused by the loss of a single enhancer. Nat Commun. 2021 Dec 13;12(1):7235

Rr496 regulates expression of:

Feature	Feature Type	Location	Reference
Pitx1, paired-like homeodomain transcription factor 1	protein coding gene	Chr13:55972864-55984005 (-)	J:268374