Rr492 Other Genome Feature Detail

Summary

• Symbol
  Rr492
• Name
  regulatory region 492
• Synonyms
  PDE, Pit, Pitx1-RA3

• Feature Type
  enhancer
• IDs
  MGI:7666150
• Regulates expression of
  Pitx1 (1 regulated gene)

Location &
Maps

• Sequence Map
  Chr13:56108910-56111397 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI
• J:264122: chr13:56,055,928-56,068,947 (mm9) chr13:56102380-56115399 (GRCm39) J:268374: chr13:56,062,458-56,064,945 (mm9) chr13:56108910-56111397 (GRCm39)

• Genetic Map
  Chromosome 13, Syntenic

Strain
Comparison

• SNPs within 2kb
  117 from dbSNP Build 142

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  3 phenotype references
  

• All Mutations and Alleles
  3
• Endonuclease-mediated
  3
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 4

  Phenotypes 3
• Earliest
  J:264122 Sarro R, et al., Disrupting the three-dimensional regulatory topology of the Pitx1 locus results in overtly normal development. Development. 2018 Apr 9;145(7):dev158550
• Latest
  J:268374 Kragesteen BK, et al., Dynamic 3D chromatin architecture contributes to enhancer specificity and limb morphogenesis. Nat Genet. 2018 Oct;50(10):1463-1473

Rr492 regulates expression of:

Feature	Feature Type	Location	Reference
Pitx1, paired-like homeodomain transcription factor 1	protein coding gene	Chr13:55972864-55984005 (-)	J:264122