Tg(Tcra,Tcrb)B5Lumc
Transgene Detail

Summary

• Symbol: Tg(Tcra,Tcrb)B5Lumc
• Name: transgene insertion B5, Leiden University Medical Centre
• MGI ID: MGI:7565757
• Transgene: Tg(Tcra,Tcrb)B5Lumc Location: unknown
• Alliance: Tg(Tcra,Tcrb)B5Lumc page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: This transgene contains a Valpha3 and Vbeta8 T cell receptor-positive T cells recognizing the H-2Db-presented Trh4 (ceramide synthase 5) epitope isolated from T cell clone LnB5. (J:231377)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:231377 Doorduijn EM, et al., TAP-independent self-peptides enhance T cell recognition of immune-escaped tumors. J Clin Invest. 2016 Feb 1;126(2):784-94
• All: 2 reference(s)