Tg(ACTA1-Slk*K63R)3405Lasa
Transgene Detail
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Symbol: |
Tg(ACTA1-Slk*K63R)3405Lasa |
Name: |
transgene insertion 3405, Luc Sabourin |
MGI ID: |
MGI:7522473 |
Synonyms: |
Tg(HSA-Slk*K63R)3405 |
Transgene: |
Tg(ACTA1-Slk*K63R)3405Lasa Location: unknown
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Alliance: |
Tg(ACTA1-Slk*K63R)3405Lasa page
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(ACTA1-Slk*K63R)3405Lasa expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Note |
mouse |
Slk (MGI:103241) |
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Tg(ACTA1-Slk*K63R)3405Lasa expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Homolog in Mouse |
Note |
human |
ACTA1 (58) |
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Mutation details: The transgene contains the human skeletal actin promoter, mouse SLK mutated gene (upstream of full-length kinase-inactive SLK bearing a point mutation at lysine 63), and HA (hemagglutinin) tag sequence. Line 654 and 3405 Tg mice have a high and low expression level of K63R, respectively.
(J:339424)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:339424 Storbeck CJ, et al., Distinct roles for Ste20-like kinase SLK in muscle function and regeneration. Skelet Muscle. 2013;3(1):16 |
All: |
1 reference(s) |
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