Tg(Gcnt1-HBEGF)3Rin
Transgene Detail

Summary

• Symbol: Tg(Gcnt1-HBEGF)3Rin
• Name: transgene insertion 3, The Tokyo Metropolitan Institute of Medical Science
• MGI ID: MGI:7514171
• Synonyms: Gsl5 TRECK Tg, Tg(Gsl5-HBEGF)3Rin
• Transgene: Tg(Gcnt1-HBEGF)3Rin Location: unknown
• Alliance: Tg(Gcnt1-HBEGF)3Rin page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Gcnt1-HBEGF)3Rin expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  HBEGF (1839)

  Hbegf

  (MGI:96070)

• Tg(Gcnt1-HBEGF)3Rin expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Gcnt1 (MGI:95676)

• Mutation details: The transgene contains the mouse Gsl5 (kidney proximal tubule-specific promoter; Gsl5, a cis-regulatory element for kidney-specific expression of the c2GnT gene) driving expression of the human Heparin-binding EGF like growth factor cDNA. (J:338608)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:338608 Sekine M, et al., The cis-regulatory element Gsl5 is indispensable for proximal straight tubule cell-specific transcription of core 2 beta-1,6-N-acetylglucosaminyltransferase in the mouse kidney. J Biol Chem. 2006;281(2):1008-15
• All: 1 reference(s)