Tg(CAG-Plce1,-lacZ)ATkat
Transgene Detail

Summary

• Symbol: Tg(CAG-Plce1,-lacZ)ATkat
• Name: transgene insertion A, Tohru Kataoka
• MGI ID: MGI:7509581
• Synonyms: Tg(CAG-xstopx-Plce1,-lacZ)ATkat
• Transgene: Tg(CAG-Plce1,-lacZ)ATkat Location: unknown
• Alliance: Tg(CAG-Plce1,-lacZ)ATkat page

Transgene origin

• Strain of Origin: B6.129X1-Pcp2^tm1(cre)Nobs/Nobs

Transgene description

• Transgene Type: Transgenic (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Mutation details: The transgene contains a CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA), Phage P1 loxP sites, STOP sequence contained a 550-bp C-terminal sequence of yeast His3 gene, mouse Plce1 cDNA, Encephalomyocarditis virus (EMCV) internal ribosomal entry site (ires), Simian virus 40 Large T antigen nuclear localization signal (NLS), E.coli lacZ, and SV40 polyA signal. (J:174654)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:174654 Takenaka N, et al., Overexpression of phospholipase Cepsilon in keratinocytes upregulates cytokine expression and causes dermatitis with acanthosis and T-cell infiltration. Eur J Immunol. 2011 Jan;41(1):202-13
• All: 1 reference(s)