Tg(Mt1-Kit*V620A)1Takk
Transgene Detail

Summary

• Symbol: Tg(Mt1-Kit*V620A)1Takk
• Name: transgene insertion 1, Takahiro Kunisada
• MGI ID: MGI:7495557
• Synonyms: Tg(MT1-Kit*VAL620ALA)1
• Transgene: Tg(Mt1-Kit*V620A)1Takk Location: unknown
• Alliance: Tg(Mt1-Kit*V620A)1Takk page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2J)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Mt1-Kit*V620A)1Takk expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Kit (MGI:96677)

• Tg(Mt1-Kit*V620A)1Takk expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Mt1 (MGI:97171)

• Mutation details: The transgene contains mouse c-kit cDNA (Val 620 Ala), mouse Mt1 promoter, human growth hormone poly A, and 5' and 3' flanking regions of mouse MT gene. Lines 1 and 4 were generated. (J:108381)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:108381 Tosaki H, et al., Mice transgenic for Kit(V620A): recapitulation of piebaldism but not progressive depigmentation seen in humans with this mutation. J Invest Dermatol. 2006 May;126(5):1111-8
• All: 2 reference(s)