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Del(11Hnf1b-Znhit3)11Moro Cytogenetic Marker Detail
Summary
  • Symbol
    Del(11Hnf1b-Znhit3)11Moro
  • Name
    deletion, Chr 11, Eric Morrow
  • Feature Type
    chromosomal deletion
  • IDs
    MGI:7490276
Location &
Maps
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  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 11, Syntenic
Human Diseases
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  • Diseases
    1 with Del(11Hnf1b-Znhit3)11Moro mouse models

Human Disease Mouse Models
      
IDs
View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    73 phenotypes from 1 allele in 2 genetic backgrounds
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice heterozygous for this deletion exhibit lethal abnormalities in head, craniofacial, and forebrain development on an inbred C57BL/6N background and similar, but less penetrant and milder, craniofacial and brain abnormalities on the outbred CD-1 background with additional defects in renal development and glucose homeostasis.
References
more
  • Summaries
    All 2
    Diseases 1
    Phenotypes 1
  • Earliest
    J:334297 Warren EB, et al., 17q12 deletion syndrome mouse model shows defects in craniofacial, brain and kidney development, and glucose homeostasis. Dis Model Mech. 2022 Dec 1;15(12):dmm049752

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/30/2025
MGI 6.24
The Jackson Laboratory