Tg(CAG-EGFP,-Aicda)20Hon
Transgene Detail

Summary

• Symbol: Tg(CAG-EGFP,-Aicda)20Hon
• Name: transgene insertion 20, Tasuku Honjo
• MGI ID: MGI:7490229
• Synonyms: Aicda^tg, AID cTg
• Transgene: Tg(CAG-EGFP,-Aicda)20Hon Location: unknown
• Alliance: Tg(CAG-EGFP,-Aicda)20Hon page

Transgene origin

• Strain of Origin: C57BL/6NCrSlc

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Mutation details: Expression of EGFP in most tissues is under control of CAG promoter. When crossed with a Cre recombinase-expressing strain, GFP expression is replaced with mouse Aicda expression in tissues expressing Cre. (J:107317)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:107317 Muto T, et al., Negative regulation of activation-induced cytidine deaminase in B cells. Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2752-7
• All: 6 reference(s)