Rr427 Other Genome Feature Detail

Summary

• Symbol
  Rr427
• Name
  regulatory region 427
• Synonyms
  +42^Mkb, Cebpa +37

• Feature Type
  enhancer
• IDs
  MGI:7489564

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.
• chr7:34855961-34856344 (GRCm39)

• Genetic Map
  Chromosome 7, Syntenic

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  6 phenotype references
  

• All Mutations and Alleles
  5
• Endonuclease-mediated
  4
• Targeted
  1
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 7

  Phenotypes 6
• Earliest
  J:294260 Guo H, et al., In Vivo Deletion of the Cebpa +37 kb Enhancer Markedly Reduces Cebpa mRNA in Myeloid Progenitors but Not in Non-Hematopoietic Tissues to Impair Granulopoiesis. PLoS One. 2016;11(3):e0150809
• Latest
  J:372692 Chen J, et al., C/EBPalpha activates Irf8 expression in myeloid progenitors at the +56-kb enhancer to initiate cDC1 development. Sci Immunol. 2025 May 16;10(107):eadt5899