Rr427 Other Genome Feature Detail

Summary

• Symbol
  Rr427
• Name
  regulatory region 427
• Synonyms
  +42^Mkb, Cebpa +37

• Feature Type
  enhancer
• IDs
  MGI:7489564

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.
• chr7:34855961-34856344 (GRCm39)

• Genetic Map
  Chromosome 7, Syntenic

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  5 phenotype references
  

• All Mutations and Alleles
  5
• Endonuclease-mediated
  4
• Targeted
  1
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 6

  Phenotypes 5
• Earliest
  J:294260 Guo H, et al., In Vivo Deletion of the Cebpa +37 kb Enhancer Markedly Reduces Cebpa mRNA in Myeloid Progenitors but Not in Non-Hematopoietic Tissues to Impair Granulopoiesis. PLoS One. 2016;11(3):e0150809
• Latest
  J:354615 Kim S, et al., Transcription factor C/EBPalpha is required for the development of Ly6C(hi) monocytes but not Ly6C(lo) monocytes. Proc Natl Acad Sci U S A. 2024 Apr 9;121(15):e2315659121