Rr401 Other Genome Feature Detail

Summary

• Symbol
  Rr401
• Name
  regulatory region 401
• Synonyms
  EnP, PE

• Feature Type
  enhancer
• IDs
  MGI:7447479

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.
• chr2:38585614-38586104 (GRCm39)

• Genetic Map
  Chromosome 2, Syntenic

Human Diseases

• Diseases
  2 with Rr401 mouse models

Human Disease

Mouse Models

infertility

IDs

infertility      

DOID:5223
MESH:D007246
NCI:C3836
UMLS_CUI:C0021359

View 1 model

Mouse Models

Human Disease Modeled: infertility

Allelic Composition	Genetic Background	Reference	Phenotypes
Rr401em1Yushi/Rr401em1Yushi	Not Specified	J:334319	View

male infertility

IDs

male infertility      

DOID:12336
ICD10CM:N46
ICD9CM:606
ICD9CM:606.9
MESH:D007248
UMLS_CUI:C0021364

View 1 model

Mouse Models

Human Disease Modeled: male infertility

Allelic Composition	Genetic Background	Reference	Phenotypes
Rr401em1Yushi/Rr401em1Yushi	Not Specified	J:334319	View

Click on a disease name to see all genes associated with that disease.

• Mutations/Alleles
  1 with disease annotations

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  19 phenotypes from 1 allele in 1 genetic background
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Endonuclease-mediated
  1
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 3

  Diseases 1

  Phenotypes 1
• Earliest
  J:136879 Shima Y, et al., Pituitary Homeobox 2 Regulates Adrenal4 Binding Protein/Steroidogenic Factor-1 Gene Transcription in the Pituitary Gonadotrope through Interaction with the Intronic Enhancer. Mol Endocrinol. 2008 Jul;22(7):1633-46
• Latest
  J:334319 Shima Y, et al., Intronic Enhancer Is Essential for Nr5a1 Expression in the Pituitary Gonadotrope and for Postnatal Development of Male Reproductive Organs in a Mouse Model. Int J Mol Sci. 2022 Dec 22;24(1)