Tg(Dmp1-SOST)1Btm
Transgene Detail

Summary

• Symbol: Tg(Dmp1-SOST)1Btm
• Name: transgene insertion 1, Teresita Bellido
• MGI ID: MGI:7444919
• Synonyms: DMP1-SOST
• Transgene: Tg(Dmp1-SOST)1Btm Location: unknown
• Alliance: Tg(Dmp1-SOST)1Btm page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Dmp1-SOST)1Btm expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SOST (50964)

  Sost	(MGI:1921749)

• Mutation details: The mouse Dmp1 promoter drives expression of a human SOST cDNA. At the 3' end, the construct also contains the140-bp fragment of the rabbit beta-globin polyadenylation sequence. (J:180217)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:180217 Tu X, et al., Sost downregulation and local Wnt signaling are required for the osteogenic response to mechanical loading. Bone. 2012 Jan;50(1):209-17
• All: 6 reference(s)