Ts(17¹⁶)66Yah Cytogenetic Marker Detail

Summary

• Symbol
  Ts(17¹⁶)66Yah
• Name
  trisomy, Chr 16 translocation to Chr 17, Yann Herault 66

• Feature Type
  unclassified cytogenetic marker
• IDs
  MGI:7408095

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 17, Syntenic

Human Diseases

• Mutations/Alleles
  1 with disease annotations

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  8 phenotypes from multigenic genotypes
  2 phenotype references
  

• All Mutations and Alleles
  1
• Endonuclease-mediated
  1
• Find Mice (IMSR)
  1 strains or lines available

References

• Summaries
  All 2

  Diseases 1

  Phenotypes 2
• Earliest
  J:331897 Duchon A, et al., Ts66Yah, a mouse model of Down syndrome with improved construct and face validity. Dis Model Mech. 2022 Dec 1;15(12):dmm049721
• Latest
  J:335240 Guedj F, et al., The Impact of Mmu17 Non-Hsa21 Orthologous Genes in the Ts65Dn Mouse Model of Down Syndrome: The Gold Standard Refuted. Biol Psychiatry. 2023 Mar 14;