Tg(HTT*/EGFP)120Nn
Transgene Detail

Summary

• Symbol: Tg(HTT*/EGFP)120Nn
• Name: transgene insertion 120, Nobuyuki Nukina
• MGI ID: MGI:7382938
• Transgene: Tg(HTT*/EGFP)120Nn Location: unknown
• Alliance: Tg(HTT*/EGFP)120Nn page

Transgene origin

• Strain of Origin: C57BL/6 x DBA/2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Tg(HTT*/EGFP)120Nn expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  HTT (3064)

  Htt	(MGI:96067)

• Mutation details: The human HTT promoter and exon 1, containing expanded CAG repeats, were fused to EGFP. This line (with about 120 repeats) was derived from the parental line containing about 190 repeats. (J:174269)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:174269 Kotliarova S, et al., Decreased expression of hypothalamic neuropeptides in Huntington disease transgenic mice with expanded polyglutamine-EGFP fluorescent aggregates. J Neurochem. 2005 May;93(3):641-53
• All: 2 reference(s)