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Rr308 Other Genome Feature Detail
Summary
  • Symbol
    Rr308
  • Name
    regulatory region 308
  • Synonyms
    Ealpha
  • Feature Type
    enhancer
  • IDs
    MGI:7378196
  • Regulates expression of
    Tcra (1 regulated gene)
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • chr14:54464810-54465046 (GRCm39)
  • Genetic Map
    Chromosome 14, Syntenic
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 3 alleles in 2 genetic backgrounds
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
References
more
  • Summaries
    All 15
    Phenotypes 15
  • Earliest
    J:82616 Sleckman BP, et al., Function of the TCR alpha enhancer in alphabeta and gammadelta T cells. Immunity. 1997 Oct;7(4):505-15
  • Latest
    J:364828 Naik AK, et al., RORgammat up-regulates RAG gene expression in DP thymocytes to expand the Tcra repertoire. Sci Immunol. 2024 Mar 15;9(93):eadh5318
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory