Tg(EEF1A1-IL15RA)1Nsat
Transgene Detail

Summary

• Symbol: Tg(EEF1A1-IL15RA)1Nsat
• Name: transgene insertion 1, Noriko Sato
• MGI ID: MGI:6867798
• Synonyms: IL-15Ralpha Tg
• Transgene: Tg(EEF1A1-IL15RA)1Nsat Location: unknown
• Alliance: Tg(EEF1A1-IL15RA)1Nsat page

Transgene origin

• Strain of Origin: 129

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(EEF1A1-IL15RA)1Nsat expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  IL15RA (3601)

  Il15ra

  (MGI:104644)

• Mutation details: The transgenic construct contains from 5' to 3' a human EEF1A1 (eukaryotic translation elongation factor 1 alpha 1) promoter, a bovine preprolactin signal peptide, the human IL15RA (interleukin 15 receptor subunit alpha) mature coding sequence followed by an SV40 polyA signal. (J:119072)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:119072 Sato N, et al., The IL-15/IL-15Ralpha on cell surfaces enables sustained IL-15 activity and contributes to the long survival of CD8 memory T cells. Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):588-93
• All: 1 reference(s)