Tg(Prnp-MAPT*)18Toco
Transgene Detail

Summary

• Symbol: Tg(Prnp-MAPT*)18Toco
• Name: transgene insertion 18, Todd Cohen
• MGI ID: MGI:6856593
• Synonyms: PS4SE
• Transgene: Tg(Prnp-MAPT*)18Toco Location: unknown
• Alliance: Tg(Prnp-MAPT*)18Toco page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Prnp-MAPT*)18Toco expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  MAPT (4137)

  Mapt	(MGI:97180)

  proline-to-serine at codon 301 (P301S) and four serine-to-glutamate substitutions at positions 262, 293, 324, and 356 in splice isoform #2 (NM_005910.5/NP_005901.2)

• Mutation details: The transgene carries several variants predicted to change amino acid coding with a proline-to-serine at codon 301 (P301S) and four serine-to-glutamate substitutions at positions 262, 293, 324, and 356 in splice isoform #2 (NM_005910.5/NP_005901.2). (J:94077)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 1 reference(s)