Tg(tetO-Rbbp4*)DRB159Kndl
Transgene Detail

Summary

• Symbol: Tg(tetO-Rbbp4*)DRB159Kndl
• Name: transgene insertion DRB159, Eric R Kandel
• MGI ID: MGI:6832817
• Synonyms: tetO-Flag-RbAp48-DN
• Transgene: Tg(tetO-Rbbp4*)DRB159Kndl Location: unknown
• Alliance: Tg(tetO-Rbbp4*)DRB159Kndl page

Transgene origin

• Strain of Origin: (C57BL/6J x CBA/J)F2

Transgene description

• Transgene Type: Transgenic (Epitope tag, Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(tetO-Rbbp4*)DRB159Kndl expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Rbbp4 (MGI:1194912)	lacks the first 54 N-terminal aa

• Mutation details: The transgenic construct contains a tetO promoter followed by a FLAG epitope tage and the dominant negative form of Rbbp4, which lacks the first 54 N-terminal amino acid residues. (J:213461)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:213461 Pavlopoulos E, et al., Molecular mechanism for age-related memory loss: the histone-binding protein RbAp48. Sci Transl Med. 2013 Aug 28;5(200):200ra115
• All: 2 reference(s)