Del(6Tmem176b-Tmem176a)1Ced Cytogenetic Marker Detail

Summary

• Symbol
  Del(6Tmem176b-Tmem176a)1Ced
• Name
  deletion, Chr 6, Cedric Louvet 1

• Feature Type
  chromosomal deletion
• IDs
  MGI:6828967

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 6, Syntenic

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotype references
  

• All Mutations and Alleles
  1
• Endonuclease-mediated
  1
• Find Mice (IMSR)
  1 strains or lines available

References

• Summaries
  All 3

  Phenotypes 2
• Earliest
  J:314921 Lemoine A, et al., Generation of a Double KO Mouse by Simultaneous Targeting of the Neighboring Genes Tmem176a and Tmem176b Using CRISPR/Cas9: Key Steps from Design to Genotyping. J Genet Genomics. 2016;43(5):329-40
• Latest
  J:315063 Lancien M, et al., Dendritic Cells Require TMEM176A/B Ion Channels for Optimal MHC Class II Antigen Presentation to Naive CD4(+) T Cells. J Immunol. 2021 Jul 7;