Tg(Alb-TFRC/OVAL)1Pmall
Transgene Detail
|
Symbol: |
Tg(Alb-TFRC/OVAL)1Pmall |
Name: |
transgene insertion 1, Paul M Allen |
MGI ID: |
MGI:6828955 |
Synonyms: |
OVA-HEP |
Transgene: |
Tg(Alb-TFRC/OVAL)1Pmall Location: unknown
|
Alliance: |
Tg(Alb-TFRC/OVAL)1Pmall page
|
|
|
Transgene Type: |
|
Transgenic (Inserted expressed sequence) |
Mutation: |
|
Insertion
|
|
|
Tg(Alb-TFRC/OVAL)1Pmall expresses
2 genes
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
chicken |
OVAL (396058) |
|
human TFRC fused to OVAL |
human |
TFRC (7037) |
|
human TFRC fused to OVAL |
|
|
|
Mutation details: The transgenic construct contains the mouse Alb (albumin) promoter driving expression of the first 118 residues of the human transferrin receptor (TFRC; including the cytoplasmic tail and signal/ancho domain) fused to residues 139-385 of mature chicken ovalbumin cDNA and a polyA tail. The transgene expresses a membrane bound form of ovalbumin o hepatocytes.
(J:314920)
|
|
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
|
|
Original: |
J:314920 Buxbaum J, et al., Hepatitis resulting from liver-specific expression and recognition of self-antigen. J Autoimmun. 2008 Nov;31(3):208-15 |
All: |
1 reference(s) |
|