Tg(Ggt-HBEGF)1Rhrs
Transgene Detail

Summary

• Symbol: Tg(Ggt-HBEGF)1Rhrs
• Name: transgene insertion 1, Raymond Harris
• MGI ID: MGI:6771525
• Synonyms: Ggt1 DTR
• Transgene: Tg(Ggt-HBEGF)1Rhrs Location: unknown
• Alliance: Tg(Ggt-HBEGF)1Rhrs page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2)

Transgene description

• Transgene Type: Transgenic (Epitope tag, Inserted expressed sequence)
• Mutation: Insertion
• Tg(Ggt-HBEGF)1Rhrs expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  HBEGF (1839)

  Hbegf

  (MGI:96070)

• Mutation details: The transgenic construct is designed to contain a rat Ggt1 promoter directing expression of a human diphtheria toxin receptor (DTR; heparin-binding epidermal growth factor-like growth factor (HBEGF)) fused to a hemagglutinin (HA) tag and a polyadenylation (polyA) sequence. (J:193980)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:193980 Zhang MZ, et al., CSF-1 signaling mediates recovery from acute kidney injury. J Clin Invest. 2012 Dec 3;122(12):4519-32
• All: 2 reference(s)